New drug tested for Life-Threatening transplant side effect

NCT ID NCT05148299

Summary

This small, completed pilot study tested an experimental drug called pegcetacoplan in 12 adult patients. These patients developed a dangerous blood vessel complication called TA-TMA after receiving a stem cell transplant. The main goals were to understand how the drug behaves in the body and to get an early look at whether it might help control this serious condition.

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Contacts and locations

Locations

  • ASST Monza - S. Gerardo Hospital

    Monza, 20900, Italy

  • Archet 1 hospital, Department of Clinical Hematology

    Nice, 06200, France

  • Big Metropolitan Hospital Niguarda Regional Health Authority

    Milan, 20162, Italy

  • CHU de Saint-Etienne

    Saint-Priest-en-Jarez, 42270, France

  • City of Hope

    Duarte, California, 91010, United States

  • General Hospital of Athens "Evangelismos"

    Athens, 10676, Greece

  • General Hospital of Thessaloniki "G. Papanikolaou", Hematology Department - BMT Unit

    Thessaloniki, 57010, Greece

  • Hospital San Giuseppe Moscati

    Avellino, 83100, Italy

  • Mayo Clinic - Rochester

    Rochester, Minnesota, 55905, United States

  • Saint-Louis Hospital

    Paris, Paris, 75010, France

  • United Hospitals Villa Sofia Cervello

    Palermo, 90146, Italy

  • University General Hospital "Attikon"

    Athens, Chaidari, 12462, Greece

  • University Hospital Puerta de Hierro Majadahonda

    Madrid, 28222, Spain

  • University Polyclinic Foundation "Agostino Gemelli" - IRCCS

    Roma, 00168, Italy

Conditions

Explore the condition pages connected to this study.