New hope for transplant patients with rare kidney disease

NCT ID NCT04572854

First seen May 01, 2026 · Last updated May 08, 2026 · Updated 3 times

Summary

This study tested a drug called pegcetacoplan in 13 adults whose rare kidney disease (C3G or IC-MPGN) came back after a kidney transplant. The goal was to see if the drug could safely reduce signs of disease in kidney tissue. Participants received the drug or standard care, and researchers checked kidney biopsies for improvement.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CHUV

    Lausanne, 1005, Switzerland

  • CUIMC

    New York, New York, 10032, United States

  • Center Hospitalier Universitaire de Montpellier

    Montpellier, 34295 CEDEX 5, France

  • Children's Hospital Colorado

    Aurora, Colorado, 80045, United States

  • Clinical Research Center, Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo

    São Paulo, 05403-000, Brazil

  • Freeman Hospital

    Newcastle upon Tyne, NE7 7DN, United Kingdom

  • Hopital Edouard Herriot, Hospices Civils de Lyon

    Lyon, 69437, France

  • Hospital Universitario 12 de Octubre, Nephrology Department

    Madrid, 28041, Spain

  • Hospital Universitario Fundacion Favaloro

    Buenos Aires, C1093AAS, Argentina

  • Hospital de Alta Complejidad en Red El Cruce Dr. Nestor Carlos Kirchner

    San Juan Bautista, Buenos Aires, B1888AAE, Argentina

  • Imperial College Healthcare NHS Trust

    London, W12 0HS, United Kingdom

  • Irmandade da Santa Casa de Misericordia de Porto Alegre

    Porto Alegre, Rio Grande do Sul, 90020-090, Brazil

  • Istituto di Ricerche Farmacologiche Mario Negri IRCCS

    Ranica, 24020, Italy

  • Keck School of Medicine, University of Southern California

    Los Angeles, California, 900033, United States

  • Lille Regional University Hospital Center, Claude Huriez Hospital, Department of Nephrology

    Lille, 59000, France

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Mayo Clinic Arizona

    Phoenix, Arizona, 85054, United States

  • Medical University of Vienna

    Vienna, 1090, Austria

  • Monash Medical Centre

    Clayton, 3168, Australia

  • NYU Langone Health Transplant Insitute

    New York, New York, 10016, United States

  • Radbound University Medical Center

    Nijmegen, 6500 HB, Netherlands

  • Santa Casa de Misericordia de Belo Horizonte

    Belo Horizonte, CEP 30150-221, Brazil

  • The Royal Melbourne Hospital

    Parkville, Victoria, 3050, Australia

  • UPECLIN - Unidade de Pesquisa Clínica da Faculdade de Medicina de Botucatu - FMB/UNESP

    Botucatu, São Paulo, 18618-686, Brazil

  • Washington University, St.Louis

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.