Could fewer drugs make pediatric intubation safer?
NCT ID NCT07680400
First seen Jul 02, 2026 · Last updated Jul 31, 2026 · Updated 2 times
Summary
This study tests whether using a combination of two common anesthetics (propofol and sevoflurane) without additional muscle relaxants or painkillers can still provide good conditions for placing a breathing tube through the nose in children. The trial involves 160 children aged 1 to 10 having elective dental surgery. Researchers will compare this lighter drug approach to the standard method to see if it is just as effective and possibly safer.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- propofol and sevoflurane
- What this could lead to
- If successful, this approach could reduce the amount of anesthetic drugs given to children while still ensuring safe breathing tube placement.
- What could go wrong
- This is a small, early-stage trial. The reduced drug approach may not work as well as the standard method, and there is a risk of poor intubation conditions or side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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160 people
The number who actually took part.
- Started
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Jul 2026
- Finished
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Jul 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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1 year to 10 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * elective dental surgery ASA 1-3 Age 1-10 Exclusion Criteria: * anticipated difficult intubation * vocal cord pathology or disease * hoarssness
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Dragos Hospital
Istanbul, Maltepe, 34844, Turkey (Türkiye)
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