New diaphragm stimulator aims to free patients from ventilators

NCT ID NCT05998018

First seen Feb 05, 2026 · Last updated May 15, 2026 · Updated 16 times

Summary

This study tested a device that uses mild electrical pulses to stimulate the phrenic nerve, helping the diaphragm contract and potentially making it easier for patients to wean off mechanical ventilation. It included 60 adults who had been on a ventilator for at least four days and had failed at least one weaning attempt. Participants were randomly assigned to receive either standard care plus the device or standard care alone. The trial was terminated early, so results are limited.

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Contacts and locations

Locations

  • Abrazo West Campus

    Goodyear, Arizona, 85395, United States

  • Atrium Health Carolinas Medical Center

    Charlotte, North Carolina, 28203, United States

  • Chandler Regional Medical Center

    Chandler, Arizona, 85224, United States

  • Denver Health

    Denver, Colorado, 80204, United States

  • Forsyth Medical Center

    Winston-Salem, North Carolina, 27103, United States

  • Grady Memorial Hospital

    Atlanta, Georgia, 30303, United States

  • HonorHealth Research Institute

    Scottsdale, Arizona, 85260, United States

  • Houston Methodist

    Houston, Texas, 77030, United States

  • LSU Health Sciences Center at Shreveport

    Shreveport, Louisiana, 71103, United States

  • Northeast Georgia Medical Center

    Gainesville, Georgia, 30501, United States

  • Northwell South Shore University Hospital

    Bay Shore, New York, 11706, United States

  • RML Specialty Hospital

    Hinsdale, Illinois, 60521, United States

  • St. David's Healthcare

    Georgetown, Texas, 78626, United States

  • Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

  • Tulane University Medical Center

    New Orleans, Louisiana, 70112, United States

  • University at Buffalo

    Buffalo, New York, 14203, United States

  • University of Illinois Chicago

    Chicago, Illinois, 60612, United States

  • University of Louisville

    Louisville, Kentucky, 40202, United States

  • University of Michigan Health - West

    Wyoming, Michigan, 49519, United States

  • University of South Alabama

    Mobile, Alabama, 36617, United States

  • WakeMed Health

    Raleigh, North Carolina, 27610, United States

Conditions

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