Immunotherapy before surgery may lower skin cancer return risk

NCT ID NCT05496036

First seen Feb 22, 2026 · Last updated May 11, 2026 · Updated 10 times

Summary

This study tests whether giving the immunotherapy drug pembrolizumab before and after standard surgery can reduce the chance of Merkel cell carcinoma coming back. About 15 adults with resectable stage I to III cancer will receive one dose before surgery, then continue after. Researchers will measure how many tumors shrink or disappear and track side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MERKEL CELL CARCINOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Penn Medicine

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.