One-Shot knee treatment could ease arthritis pain for years

NCT ID NCT06884865

First seen Mar 26, 2026 · Last updated May 14, 2026 · Updated 7 times

Summary

This study tests a single injection of an experimental drug called PCRX-201 for people with painful knee osteoarthritis. About 135 adults aged 45 to 80 will receive either a low dose, a high dose, or a placebo to see if it is safe and helps reduce pain and improve knee function. Researchers will follow participants for up to 5 years to monitor side effects and long-term benefits.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OSTEOARTHRITIS (OA) OF THE KNEE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Alabama Clinical Therapeutics, LLC

    Birmingham, Alabama, 35235, United States

  • Alliance Clinical West Hills (Focus Clinical Research)

    West Hills, California, 91307, United States

  • Altoona Center for Clinical Research

    Duncansville, Pennsylvania, 16635, United States

  • Arrow Clinical Trials

    Daytona Beach, Florida, 32117, United States

  • Beach Physicians Medical Group Inc.

    Huntington Beach, California, 92647, United States

  • Clinical Trials of South Carolina - Charleston

    Charleston, South Carolina, 29406, United States

  • Clinical Trials of South Carolina - Columbia

    Columbia, South Carolina, 29206, United States

  • Conquest Research

    Winter Park, Florida, 32789, United States

  • Epic Clinical Research

    Lewisville, Texas, 75057, United States

  • Excel Clinical Research

    Las Vegas, Nevada, 89109, United States

  • Horizon Clinical Research

    La Mesa, California, 91942, United States

  • Journey Research Inc.

    Oldsmar, Florida, 34677-4681, United States

  • NY Scientific

    Brooklyn, New York, 11235-3919, United States

  • Osteoporosis Medical Center

    Beverly Hills, California, 90211, United States

  • Palm Beach Research Center

    West Palm Beach, Florida, 33409, United States

  • Physicians Research Collaboration

    Lincoln, Nebraska, 68516, United States

  • Zenos Clinical Research

    Dallas, Texas, 75230, United States

Conditions

Explore the condition pages connected to this study.