Could a dissolving scaffold replace silicone implants? new trial begins

NCT ID NCT07367698

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a breast scaffold made from polycaprolactone (PCL), an absorbable material, combined with the patient's own fat to reconstruct the breast after implant removal. It involves 73 women who want to revise their previous breast augmentation. The goal is to see if this approach is safe and effective, with follow-up for up to 5 years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

polycaprolactone (PCL) breast scaffold with autologous fat grafting

What this could lead to

If it works, this could offer a safer, more natural alternative to replacing silicone breast implants, using the body's own fat for reconstruction.

What could go wrong

This is an early-stage study with only 73 participants, so results may not apply to everyone. Risks include device-related side effects or the need for further surgery.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Evangelisches Krankenhaus Göttingen-Weende

    NOT_YET_RECRUITING

    Göttingen, Lower Saxony, 37075 Göttingen, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Macquarie University Hospital

    RECRUITING

    Sydney, New South Wales, 2109, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Royal Brisbane and Women's Hospital (RBWH), Herston Biofabrication Institute (HBI)

    NOT_YET_RECRUITING

    Brisbane, Queensland, 4029, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Universitätsklinikum Münster

    NOT_YET_RECRUITING

    Münster, North Rhine-Westphalia, 48149 Münster, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Westmead Hospital, Lakeview Private Hospital

    NOT_YET_RECRUITING

    Sydney, New South Wales, 2145, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Zealand University Hospital

    NOT_YET_RECRUITING

    Roskilde, Region Sjælland, 4000 Roskilde, Denmark

    Contact Email: •••••@•••••

    Contact