Can a new CT scan spot tiny gut lesions that older scans miss?
NCT ID NCT07748923
First seen Aug 06, 2026 · Last updated Aug 11, 2026 · Updated 3 times
Summary
This trial compares two types of CT scans—photon-counting CT (PCCT) and dual-energy CT (DECT)—to see which one is better at finding small gastrointestinal lesions (like tiny growths or thickening in the gut lining). About 1,700 adults who are having a contrast-enhanced abdominal CT and have at least one suspected or confirmed small lesion will be included. The study will check how often each scan detects these lesions, using endoscopy with biopsy as the gold standard, and also look at image quality and how well different doctors agree on what they see.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Contrast-enhanced photon-counting computed tomography (PCCT) compared with energy-integrating detector dual-energy CT (DECT)
- What this could lead to
- If PCCT proves more accurate, it could become the preferred imaging method for detecting small gastrointestinal lesions, potentially reducing missed diagnoses and the need for invasive procedures.
- What could go wrong
- The trial is a comparison study, not a treatment trial, so it won't directly improve outcomes. PCCT may not show a significant advantage over DECT, and its higher cost or limited availability could limit widespread adoption.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The Second Affiliated Hospital of Chongqing Medical University
Chongqing, Chongqing Municipality, 400010, China
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