Heart surgery bleeding breakthrough? new drug could replace plasma transfusions
NCT ID NCT04244981
First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 26 times
Summary
This study compares a clotting drug (prothrombin complex concentrate, or PCC) to fresh frozen plasma (FFP) for reducing blood loss in adults undergoing heart surgery. About 820 participants will receive either PCC or FFP during surgery, and their bleeding and need for blood transfusions will be tracked for a week. The goal is to see if PCC works as well as FFP, potentially offering a faster and safer option to control bleeding.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cardiovascular Institute and Fuwai Hospital, CAMS&PUMC
RECRUITINGBeijing, Beijing Municipality, 100037, China
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Peking Union Medical College Hospital
RECRUITINGBeijing, Beijing Municipality, 100730, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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