New drug duo tested to fight back against rare liver disease

NCT ID NCT05239468

Summary

This study tested whether adding a new drug called bezafibrate to an existing one (obeticholic acid) could better control Primary Biliary Changitis (PBC), a chronic liver disease. It involved 72 adults with PBC who were already on standard treatment. The main goal was to see if the drug combination improved key liver blood test results over 12 weeks.

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Contacts and locations

Locations

  • American Research Corporation at the Texas Liver Institute

    San Antonio, Texas, 78215, United States

  • Azienda Ospedaliero-Universitaria di Bologna Policlinico S. Orsola-Malpighi

    Bologna, Italy

  • Beth Israel Deaconess Medical Center Harvard Liver Research Center

    Boston, Massachusetts, 02215, United States

  • DIM Clinical Privada

    Ramos Mejía, Buenos Aires, Argentina

  • Facey Medical Group

    Mission Hills, California, 91345, United States

  • Gastro One

    Cordova, Tennessee, 38018, United States

  • Gastrointestinal Associates of Northeast Tennessee

    Johnson City, Tennessee, 37604, United States

  • Hospital Italiano La Plata

    La Plata, Buenos Aires, Argentina

  • Hospital Italiano de Buenos Aires

    Buenos Aires, Argentina

  • Hospital Provincial del Centenario

    Rosario, Argentina

  • Hospital Universitario Austral

    Pilar, Argentina

  • Houston Methodist Cancer Center

    Houston, Texas, 77030-2717, United States

  • Loyola University Medical Center

    Maywood, Illinois, 60459, United States

  • Methodist Clinical Research Institute (CRI)

    Dallas, Texas, 75203, United States

  • NYU Langone Medical Center

    New York, New York, 10016-6402, United States

  • Ochsner Medical Center

    New Orleans, Louisiana, 70121, United States

  • Pacific Gastroenterology Associates

    Vancouver, British Columbia, V6Z 2K5, Canada

  • Piedmont Atlanta Hospital

    Atlanta, Georgia, 30309, United States

  • Schiff Center for Liver Diseases / University of Miami

    Miami, Florida, 33136, United States

  • Southern California Gastrointestinal (GI) and Liver Centers (SCLC) - Coronado

    Coronado, California, 92118, United States

  • Tampa General Medical Group

    Tampa, Florida, 33606, United States

  • The Northern Alberta Clinical Trials and Research Centre

    Edmonton, Alberta, T6G 287, Canada

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35233, United States

  • University of Montreal

    Montreal, Quebec, Canada

  • Wake Endoscopy Center

    Raleigh, North Carolina, 27607, United States

Conditions

Explore the condition pages connected to this study.