Could a hidden infection explain that thickened nuchal translucency?

NCT ID NCT05388968

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether infections might be linked to increased nuchal translucency, a marker seen on early pregnancy ultrasounds. Researchers used advanced genetic sequencing to look for viruses, bacteria, or parasites in placental tissue from 78 pregnant women. The goal was to see if hidden infections could be a cause, but this was an observational study, not a treatment trial.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could show that some cases of increased nuchal translucency are caused by infections, potentially leading to new screening or treatment approaches.
What could go wrong
This is a small, completed observational study, not a treatment trial. It only looks for infections and does not test any therapy, so it cannot prove cause or offer direct benefit to participants.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hopital Necker - Enfants malades

    Paris, 75015, France