Experimental eye implant aims to halt vision loss in dry AMD

NCT ID NCT06557460

Recruiting now Disease control Sponsor: Regenerative Patch Technologies, LLC Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase IIb trial tests a retinal implant (CPCB-RPE1) in 24 people with advanced dry age-related macular degeneration (geographic atrophy). Participants are randomly assigned to receive the implant or a sham procedure. The study measures changes in retinal sensitivity and visual acuity over time to see if the implant can slow or improve vision loss.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: CPCB-RPE1 implant (a retinal cell implant)
What this could lead to: If successful, this implant could slow vision loss or improve sight in people with advanced dry AMD, offering a new treatment option.
What could go wrong: This is an early Phase IIb trial with only 24 people. The implant requires surgery, which carries risks like infection or retinal detachment. It may not work better than a sham procedure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dry age related macular degeneration Geographic Atrophy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

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Locations

Retina Associates of Southern California
RECRUITING

Huntington Beach, California, 92647, United States

Contact Email: •••••@•••••
Retina Consultants of Texas
RECRUITING

The Woodlands, Texas, 77384, United States

Contact Email: •••••@•••••
Retina-Vitreous Associates Medical Group
RECRUITING

Beverly Hills, California, 90211, United States

Contact Email: •••••@•••••
USC - Keck
RECRUITING

Los Angeles, California, 90033, United States

Contact Email: •••••@•••••
University Retina
RECRUITING

Lemont, Illinois, 60439, United States

Contact Email: •••••@•••••

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