Experimental eye implant aims to halt vision loss in dry AMD

NCT ID NCT06557460

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase IIb trial tests a retinal implant (CPCB-RPE1) in 24 people with advanced dry age-related macular degeneration (geographic atrophy). Participants are randomly assigned to receive the implant or a sham procedure. The study measures changes in retinal sensitivity and visual acuity over time to see if the implant can slow or improve vision loss.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CPCB-RPE1 implant (a retinal cell implant)

What this could lead to

If successful, this implant could slow vision loss or improve sight in people with advanced dry AMD, offering a new treatment option.

What could go wrong

This is an early Phase IIb trial with only 24 people. The implant requires surgery, which carries risks like infection or retinal detachment. It may not work better than a sham procedure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

dry age related macular degeneration Geographic Atrophy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Retina Associates of Southern California

    RECRUITING

    Huntington Beach, California, 92647, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Retina Consultants of Texas

    RECRUITING

    The Woodlands, Texas, 77384, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Retina-Vitreous Associates Medical Group

    RECRUITING

    Beverly Hills, California, 90211, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • USC - Keck

    RECRUITING

    Los Angeles, California, 90033, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Retina

    RECRUITING

    Lemont, Illinois, 60439, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••