New drug combo tested for tough cancers

NCT ID NCT06421935

First seen Nov 01, 2025 · Last updated May 17, 2026 · Updated 35 times

Summary

This early-phase study tests a new drug called M9466, alone or with other treatments, in people with advanced solid tumors that have not responded to standard therapy. The main goal is to check safety and how the drug moves through the body. About 141 participants will receive the drug until their disease worsens or side effects become too severe.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Asan Medical Center

    Seoul, South Korea

  • Cancer Institute Hospital of JFCR

    Kōtoku, Japan

  • Cancer Research SA

    Adelaide, Australia

  • Centro Integral Oncologico Clara Campal - Unidad de Fase I-Oncologica

    Madrid, Spain

  • GenesisCare North Shore (Oncology)

    St Leonards, Australia

  • Harasanshin Hospital

    Fukuoka, Japan

  • Hospital HM Nou Delfos - START Barcelona

    Barcelona, Spain

  • Hospital Universitari Vall d'Hebron - Oncology Dept.

    Barcelona, Spain

  • Hospital Universitario 12 de Octubre - Servicio de Oncologia

    Madrid, Spain

  • Hospital Universitario Fundacion Jimenez Diaz - START Madrid FJD - Oncology Phase I

    Madrid, Spain

  • ICO l'Hospitalet - Hospital Duran i Reynals - Servicio de Oncologia

    Barcelona, Spain

  • NEXT Madrid - Hospital Universitario Quironsalud Madrid

    Pozuelo de Alarcón, Spain

  • NEXT Oncology - PARENT

    New York, New York, 10065, United States

  • NHO Kumamoto Medical Center - Dept of Urology

    Kumamoto, Japan

  • National Cancer Center Hospital East - Dept of Experimental Therapeutics

    Kashiwa-shi, Japan

  • Samsung Medical Center

    Seoul, South Korea

  • Seoul National University Bundang Hospital

    Seongnam, South Korea

  • Seoul National University Hospital

    Seoul, South Korea

  • Severance Hospital, Yonsei University Health System - Division of Infectious Diseases

    Seoul, South Korea

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.