New device plugs dangerous heart valve leaks without open surgery
NCT ID NCT04489823
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a special plug device to close leaks that can form around surgically implanted heart valves. These leaks can cause serious problems like heart failure or anemia. The procedure is done through a catheter, avoiding the need for another open-heart surgery. The study includes 200 adults with moderate or worse leaks and aims to see if the device is safe and effective.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PARAVALVULAR AORTIC REGURGITATION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Baptist Memorial Hospital
Memphis, Tennessee, 38120, United States
-
Carilion Roanoke Memorial Hospital
Roanoke, Virginia, 24014, United States
-
Edinburgh Heart Centre
Edinburgh, Lothian, EH16 4SA, United Kingdom
-
Emory University Hospital
Atlanta, Georgia, 30322, United States
-
Gornoslaskie Centrum Medyczne im.prof. Leszka Gieca
Katowice, Silesian Voivodeship, 40-635, Poland
-
Hackensack University Medical Center
Hackensack, New Jersey, 07601, United States
-
Hospital Ramón y Cajal
Madrid, Madrid, 28034, Spain
-
Hospital Universitario de Salamanca
Salamanca, Spain
-
Institut de Cardiologie de Montreal (Montreal Heart Inst.)
Montreal, Quebec, H1T 1C8, Canada
-
Institut de Cardiologie de Quebec (Hôpital Laval)
Québec, Quebec, G1V 4G5, Canada
-
Intermountain Medical Center
Murray, Utah, 84157, United States
-
Lenox Hill Hospital
New York, New York, 10021, United States
-
Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
-
Minneapolis Heart Institute
Minneapolis, Minnesota, 55407, United States
-
New York Presbyterian Hospital/Cornell University
New York, New York, 10021, United States
-
Ospedale San Raffaele
Milan, Lombard, 20132, Italy
-
Papworth Hospital NHS Foundation Trust
Cambridge, United Kingdom
-
Providence Sacred Heart Medical Center
Spokane, Washington, 99202, United States
-
Saint Luke's Hospital of Kansas City
Kansas City, Missouri, 64111, United States
-
St. Antonius Ziekenhuis
Nieuwegein, Utrecht, 3435 CM, Netherlands
-
The Cleveland Clinic Foundation
Cleveland, Ohio, 44195, United States
-
The Royal Sussex County Hospital
Brighton, Soeast, BN25BE, United Kingdom
-
University Hospital - Univ. of Alabama at Birmingham (UAB)
Birmingham, Alabama, 35249, United States
-
University of Nebraska Medical Center
Omaha, Nebraska, 68198, United States