Common painkillers may cut opioid use after nose surgery

NCT ID NCT07337629

First seen Jan 14, 2026 · Last updated Jun 19, 2026 · Updated 19 times

Summary

This study compares giving a single dose of paracetamol or ibuprofen before septorhinoplasty (nose surgery) to see if it reduces the amount of opioid painkillers needed during and after surgery. Researchers will track total opioid use, pain scores, and recovery quality in 54 adults. The goal is to find a simple way to lessen opioid reliance.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Samsun University Samsun Training and Research Hospital

    RECRUITING

    Samsun, Turkey (Türkiye)

    Contact Phone: •••-•••-••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

paracetamol and ibuprofen

What this could lead to

If it works, this could show that a single dose of common painkillers before surgery can reduce the need for stronger opioid painkillers afterward.

What could go wrong

This is a small, early-stage trial with only 54 participants, so results may not apply to everyone. It tests a well-known approach, so no major breakthrough is expected.

Conditions

The condition(s) this trial relates to.

agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.