New mRNA flu vaccine shows promise in early human trial

NCT ID NCT06602531

First seen Oct 31, 2025 · Last updated May 12, 2026 · Updated 25 times

Summary

This early-stage study tested a new self-amplifying mRNA vaccine (ARCT-2304) designed to protect against pandemic influenza in 212 healthy adults aged 18-80. Participants received either two doses of the experimental vaccine or one dose of a licensed flu vaccine plus a placebo. Researchers monitored side effects and measured immune responses to find the safest and most effective dose for further testing.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CTI Clinical Research Center

    Cincinnati, Ohio, 45212, United States

  • Tekton Research

    Longmont, Colorado, 80501, United States

  • Velocity Clinical Research

    La Mesa, California, 91942, United States

  • Velocity Clinical Research

    San Bernardino, California, 92408, United States

Conditions

Explore the condition pages connected to this study.