New enzyme test may catch pancreatic leaks earlier

NCT ID NCT02784990

First seen Feb 06, 2026 · Last updated May 15, 2026 · Updated 11 times

Summary

This study looked at 770 adults who had pancreas surgery to see if measuring an enzyme called lipase in their surgical drains could help doctors spot a common complication called pancreatic fistula earlier. A pancreatic fistula is a leak of digestive juices that can cause serious infections or bleeding. The researchers collected drain fluid and blood samples at several time points after surgery to compare lipase levels with the standard test (amylase). The goal was to find a more accurate way to detect fistulas that need treatment, potentially preventing more severe problems.

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Contacts and locations

Locations

  • APHM - Institut Paoli-Calmettes

    Marseille, 13009, France

  • CHU Dijon Bourgogne

    Dijon, 21079, France

  • CHU Grenoble Alpes

    La Tronche, 38700, France

  • CHU Jean Minjoz

    Besançon, 25030, France

  • CHU William MOREY

    Chalon-sur-Saône, 71321, France

  • CHU de NANCY

    Vandœuvre-lès-Nancy, 54511, France

  • CHU de REIMS - Hôpital Robert Debré

    Reims, 51100, France

  • HCL - Hôpital universitaire de la Croix Rousse

    Lyon, 69317, France

  • Hopital Claude Huriez

    Lille, 59037, France

  • Hôpital Hautepierre

    Strasbourg, 67098, France

Conditions

Explore the condition pages connected to this study.