New hope for pancreatic cancer: experimental drug combo enters human trials

NCT ID NCT07114861

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial is testing whether adding two experimental drugs (KN510 and KN713) to standard chemotherapy (mFOLFIRINOX) is safe and effective for people with advanced pancreatic cancer that cannot be removed by surgery. About 30 adults aged 19–75 who have not had prior chemo for advanced disease will take part. The study will first find the best dose, then expand to see how well the combination controls tumor growth.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

KN510713 (two experimental drugs) plus mFOLFIRINOX chemotherapy

What this could lead to

If successful, this combination could offer a new treatment option for advanced pancreatic cancer, potentially shrinking tumors or slowing disease progression.

What could go wrong

This is an early-phase trial with only 30 participants, so results may not apply broadly. The experimental drugs could cause side effects or fail to improve outcomes over standard chemo alone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

pancreatic ductal adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Cancer Center

    RECRUITING

    Goyang-si, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••