New hope for pancreatic cancer: experimental drug combo enters human trials

NCT ID NCT07114861

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial is testing whether adding two experimental drugs (KN510 and KN713) to standard chemotherapy (mFOLFIRINOX) is safe and effective for people with advanced pancreatic cancer that cannot be removed by surgery. About 30 adults aged 19–75 who have not had prior chemo for advanced disease will take part. The study will first find the best dose, then expand to see how well the combination controls tumor growth.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
KN510713 (two experimental drugs) plus mFOLFIRINOX chemotherapy
What this could lead to
If successful, this combination could offer a new treatment option for advanced pancreatic cancer, potentially shrinking tumors or slowing disease progression.
What could go wrong
This is an early-phase trial with only 30 participants, so results may not apply broadly. The experimental drugs could cause side effects or fail to improve outcomes over standard chemo alone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Cancer Center

    RECRUITING

    Goyang-si, South Korea