New combo targets tough pancreatic cancer in 40-patient trial

NCT ID NCT07240766

First seen Nov 21, 2025 · Last updated May 06, 2026 · Updated 20 times

Summary

This study tests a new drug combination (HRS-4642, nimotuzumab, and chemotherapy) in 40 people with a specific type of pancreatic cancer that has a KRAS G12D mutation and is borderline removable. The goal is to see if this treatment can shrink tumors enough for successful surgery and improve survival. Participants must not have had prior cancer therapy and must be between 18 and 75 years old.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • First Affiliated Hospital of Zhejiang University Schlool of Medicine

    NOT_YET_RECRUITING

    Hangzhou, Zhejiang, 310000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • the First Affiliated Hospital of Zhejiang University, School of Medicine

    RECRUITING

    Hangzhou, Zhejiang, 310000, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.