New combo targets tough pancreatic cancer gene

NCT ID NCT06770452

First seen Nov 01, 2025 · Last updated Jun 13, 2026 · Updated 27 times

Summary

This study tests a new drug combination (HRS-4642, nimotuzumab, and chemotherapy) as a first treatment for people with advanced pancreatic cancer that has a specific KRAS G12D mutation. About 32 participants will receive the combination to see how many respond. The goal is to control the disease, not cure it, as ongoing management is expected.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for METASTATIC PANCREATIC CARCINOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • First Affiliated Hospital of Zhejiang University Schlool of Medicine

    NOT_YET_RECRUITING

    Hangzhou, Zhejiang, 310000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Zhejiang University School of Medicine

    RECRUITING

    Hangzhou, Zhejiang, 310000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.