Mini-Tumors in a dish may guide pancreatic cancer treatment

NCT ID NCT07683845

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This study investigates whether tiny, lab-grown copies of a patient's own pancreatic tumor—called organoids—can predict how well standard chemotherapy will work. Researchers will collect tumor samples from 164 people with pancreatic cancer, grow organoids from them, and test different chemotherapy drugs in the lab. The results will be compared to how each patient actually responds to treatment. If the organoid tests match clinical outcomes, this could lead to a personalized tool that helps doctors pick the right chemotherapy from the start, avoiding ineffective treatments and their side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this approach could help doctors choose the most effective chemotherapy for each pancreatic cancer patient, reducing trial-and-error and improving outcomes.
What could go wrong
This is an observational study, not a treatment trial. The organoid test may not accurately predict real patient responses, and results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ruijin Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, 200025, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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