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New hope for pancreatic cancer: drug combo shows promise in early trial

NCT ID NCT06225999

Completed Disease control Sponsor: Institut de Recherches Internationales Servier Source: ClinicalTrials.gov ↗

First seen May 15, 2026 · Last updated May 15, 2026

Summary

This study tested a combination of four drugs (irinotecan liposome, oxaliplatin, 5-FU, and leucovorin) in 41 Japanese adults with advanced pancreatic cancer that had not been treated before. The goal was to see if the treatment could shrink tumors and to check its safety. Participants received the drugs on days 1 and 15 of each 28-day cycle until their disease got worse or side effects became too severe.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Aichi Cancer Center (007)

    Nagoya, 464-8681, Japan

  • Chiba Cancer Center (011)

    Chiba, 260-8717, Japan

  • Chiba University Hospital (015)

    Chiba, 260-8677, Japan

  • Hokkaido University Hospital (004)

    Sapporo, 060-8648, Japan

  • Kanagawa Cancer Center (002)

    Kanagawa, 241-8515, Japan

  • Kanazawa University Hospital (008)

    Ishikawa, 920-8641, Japan

  • National Cancer Center Hospital (001)

    Tokyo, 104-0045, Japan

  • National Cancer Center Hospital East (003)

    Kashiwa, Chiba, 277-8577, Japan

  • National Hospital Organization Kyushu Cancer Center (005)

    Fukuoka, 811-1395, Japan

  • National Hospital Organization Shikoku Cancer Center (013)

    Ehime, 791-0280, Japan

  • Osaka International Cancer Institute (009)

    Osaka, 541-8567, Japan

  • Saitama Cancer Center (012)

    Saitama, 362-0806, Japan

  • The Cancer Institute Hospital of JFCR (006)

    Tokyo, 135-8550, Japan

  • Yamaguchi University Hospital (010)

    Yamaguchi, 755-8505, Japan

Conditions

Explore the condition pages connected to this study.

METASTATIC ADENOCARCINOMA OF THE PANCREAS