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Could teaching the brain about pain be the key to relief?

NCT ID NCT07788781

Symptom relief Sponsor: University of Vigo Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 26, 2026 · Last updated Aug 27, 2026 · Updated 1 time

Summary

This pilot trial explores whether adding pain neuroscience education to a therapeutic exercise program can reduce pain intensity in adults with chronic musculoskeletal pain. Participants are randomly assigned to receive either exercise plus education or exercise alone over eight weeks. The study also looks at effects on fear of movement, beliefs about pain, and muscle strength, and aims to inform a larger future trial.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Pain neuroscience education combined with therapeutic exercise
What this could lead to
If effective, this approach could offer a non-drug way to reduce chronic pain and fear of movement, potentially improving quality of life.
What could go wrong
This is a small pilot study, so results may not be conclusive. The added benefit of education over exercise alone is uncertain, and individual responses may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

38 people

The number who actually took part.

Started

May 2026

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age \>18 years. * Chronic musculoskeletal pain lasting more than 3 months, regardless of pain location. * Provision of written informed consent to participate in the study. Exclusion Criteria: * Psychiatric or psychological condition that could interfere with the performance or understanding of the therapeutic exercise program or the educational intervention. * Degenerative neurological disease or neurological disease affecting the central nervous system. * Recent surgery. * Pregnancy.

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Conditions

The condition(s) this trial relates to.

Chronic Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic musculoskeletal pain

Contacts and locations

Locations

  • Studio Pilates Fisioterapia

    Pontevedra, Pontevedra, 36005, Spain

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