New pain relief combo aims to get bowels moving faster after surgery

NCT ID NCT07651722

First seen Jun 17, 2026 · Last updated Jun 22, 2026 · Updated 1 time

Summary

This study tests whether a combination of a long-acting numbing drug (liposomal bupivacaine) injected into the abdominal wall and a painkiller (oxycodone) given through an IV can help the gut recover faster after major abdominal surgery. The trial will enroll 132 adults having small bowel or colorectal surgery. Participants will be split into three groups to compare different pain relief methods, with the main goal being better bowel function in the first week after surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • Tianjin First Central Hospital

    Tianjin, Tianjin Municipality, 300384, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

liposomal bupivacaine and oxycodone

What this could lead to

If it works, this could lead to a standard pain management approach that helps patients recover bowel function faster after abdominal surgery.

What could go wrong

This is a small, early-stage trial that hasn't started yet. The new combination may not work better than existing options, and any painkiller carries risks like nausea or breathing problems.

Conditions

The condition(s) this trial relates to.

Pain, Postoperative paralytic ileus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.