Can less pain meds mean better spinal stimulation? new study investigates

NCT ID NCT07502612

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study looks at how lowering doses of pain medications like opioids and gabapentinoids changes the way the spinal cord responds to closed-loop spinal cord stimulation. Twenty adults with failed back surgery syndrome will be followed during a 21-day trial and up to 6 months after a permanent implant. The goal is to understand the relationship between medication tapering and spinal cord sensitivity, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Closed-loop spinal cord stimulation (Evoke system)

What this could lead to

If successful, this study could help doctors understand how to safely reduce pain medication while using spinal cord stimulation to manage chronic back pain.

What could go wrong

This is a very small pilot study with only 20 participants, so results may not apply to everyone. It is designed to gather information, not to prove a treatment works.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

complex regional pain syndrome type 2 Failed Back Surgery Syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brai²n - ZAS Augustinus

    RECRUITING

    Wilrijk, 2610, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact