New study seeks clues to who gets PAH and who stays healthy
NCT ID NCT05584722
First seen Mar 19, 2026 · Last updated Jun 20, 2026 · Updated 18 times
Summary
This study follows 150 people, including those with pulmonary arterial hypertension (PAH), healthy carriers of a PAH-related gene mutation, and healthy controls. Researchers will track changes in quality of life, exercise ability, heart and lung function, and daily activity over up to 32 months. The goal is to uncover molecular signatures that explain why some people develop PAH while others remain healthy, potentially pointing to new treatment targets.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Vanderbilt University Medical Center
RECRUITINGNashville, Tennessee, 37232, United States
Contact Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could identify new targets for future treatments and help predict who is at risk for PAH.
What could go wrong
This is an observational study, not a treatment trial. It will not directly benefit participants and may not lead to new therapies.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.