New pacemaker technique could improve outcomes for heart rhythm patients

NCT ID NCT07314008

Recruiting now Disease control Sponsor: Asan Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two pacemaker strategies for people with sick sinus syndrome and AV conduction delay. Participants will be randomly assigned to receive either left bundle branch area pacing (LBBAP) or minimized ventricular pacing (MVP). The goal is to see which method leads to fewer deaths, heart failure hospitalizations, or persistent atrial fibrillation. About 440 adults will take part across multiple centers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Left bundle branch area pacing (LBBAP) device
What this could lead to: If successful, this could show that LBBAP is a better pacing method for people with certain heart rhythm problems, potentially reducing complications like heart failure or atrial fibrillation.
What could go wrong: This is an early-stage comparison study, not a large-scale trial. The benefits may not be significant, and device implantation carries risks like infection or lead displacement.

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Conditions

The condition(s) this trial relates to.

atrioventricular block atrioventricular node disorder sick sinus syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIOVENTRICULAR NODAL DYSFUNCTION SICK SINUS SYNDROME

Contacts and locations

Locations

Asan Medical Center
RECRUITING

Seoul, Songpa-gu, 05505, South Korea

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