New pacemaker technique could improve outcomes for heart rhythm patients

NCT ID NCT07314008

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two pacemaker strategies for people with sick sinus syndrome and AV conduction delay. Participants will be randomly assigned to receive either left bundle branch area pacing (LBBAP) or minimized ventricular pacing (MVP). The goal is to see which method leads to fewer deaths, heart failure hospitalizations, or persistent atrial fibrillation. About 440 adults will take part across multiple centers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Left bundle branch area pacing (LBBAP) device

What this could lead to

If successful, this could show that LBBAP is a better pacing method for people with certain heart rhythm problems, potentially reducing complications like heart failure or atrial fibrillation.

What could go wrong

This is an early-stage comparison study, not a large-scale trial. The benefits may not be significant, and device implantation carries risks like infection or lead displacement.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atrioventricular block atrioventricular node disorder sick sinus syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Asan Medical Center

    RECRUITING

    Seoul, Songpa-gu, 05505, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••