New combo treatment aims to smooth Crow's feet without surgery

NCT ID NCT07222176

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether using a peptide-based cream (P-TIOX) alongside a heat-based skin treatment (Tixel) reduces fine lines around the eyes better than the heat treatment alone. Twenty adults aged 30 and older with moderate to severe wrinkles will receive both treatments on one side of the face and only the heat treatment on the other. The study lasts about 9 weeks and uses photos and expert ratings to measure results.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
P-TIOX (a peptide-based cosmeceutical cream) and Tixel (a heat-based skin treatment device)
What this could lead to
If it works, this could point toward a more effective non-surgical option for reducing fine lines around the eyes.
What could go wrong
This is a very small, early-stage study with only 20 people. Results may not apply to everyone, and the improvement might be minor or not noticeable.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Main Line Center for Laser Surgery

    Ardmore, Pennsylvania, 19107, United States