Cure My Disease

Don't miss your cure!

 Log in / Sign up

Ozone gas may boost bone levels around dental implants

NCT ID NCT07687641

Disease control Sponsor: Adiyaman University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 07, 2026 · Last updated Sep 09, 2026 · Updated 6 times

Summary

This study tests whether applying ozone gas to the implant socket before placing a dental implant helps preserve bone around the implant. Adults needing two implants in different jaw areas receive ozone at one site and standard treatment at the other. Bone levels are measured with 3D scans over six months to see if ozone improves healing.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Gaseous ozone
What this could lead to
If ozone treatment improves bone healing around implants, it could lead to better long-term implant stability and reduced bone loss.
What could go wrong
This is a small, early-stage study with 50 participants, so results may not apply to everyone. Ozone application is a procedure, and its benefits over standard care are not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

50 people

The number who actually took part.

Started

Sep 2025

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 to 65 years. * Systemically healthy individuals. * Ability to comply with the study procedures and follow-up visits. * Requirement for implant placement at matched contralateral posterior sites within the same jaw. * Healed edentulous sites suitable for conventional implant placement. * Adequate alveolar bone volume for placement of implants measuring 3.5-4.0 mm in diameter and 8-12 mm in length without the need for advanced bone augmentation, with at least 1.5 mm of surrounding bone. * Initial soft-tissue thickness of at least 2 mm and keratinized mucosal width of at least 2 mm at the implant sites. * Provision of written informed consent. Exclusion Criteria: * Systemic diseases or medical conditions contraindicating implant surgery. * Pregnancy. * Smoking. * Active oral infection or advanced periodontal disease. * Insufficient bone volume requiring advanced bone augmentation. * Incomplete healing at the intended implant site following recent tooth extraction. * Previous implant failure at the intended implant site. * Any contraindication to ozone therapy.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Dental implantation are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Alveolar Bone Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dental implantation Effects of gaseous ozone on marginal bone levels Immediate dental implant placement Peri-implant marginal bone loss

Contacts and locations

Locations

  • Faculty of Dentistry, Adıyaman University

    Adıyaman, Merkez, 02030, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.