Less oxygen during surgery may protect lungs in elderly patients
NCT ID NCT06359106
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares giving 40% versus 80% oxygen during laparoscopic gastrointestinal surgery in patients aged 65 and older. The goal is to see which oxygen level leads to better lung function after surgery. Over 1,100 participants will be randomly assigned to one of the two oxygen levels, and their oxygen levels and lung complications will be tracked for 7 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- inhaled oxygen (40% or 80% concentration)
- What this could lead to
- If it works, this could show that using less oxygen during surgery is safer for older patients' lungs, leading to better recovery guidelines.
- What could go wrong
- This is a phase 4 trial comparing two standard oxygen levels, so it's not testing a new treatment. The results may only apply to older patients having specific laparoscopic surgery, and the difference between groups might be small.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Affiliated Hospital of Qingdao University
RECRUITINGQingdao, China
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Beijing Friendship Hospital, Capital Medical University
RECRUITINGBeijing, China
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Chifeng Municipal Hospital
RECRUITINGChifeng, China
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Dalian Third People's Hospital
RECRUITINGDalian, China
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First Affiliated Hospital of Harbin Medical University
RECRUITINGHarbin, China
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First Affiliated Hospital of Kunming Medical University
RECRUITINGKunming, China
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First Affiliated Hospital, Dalian Medical University
RECRUITINGDalian, China
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First Hospital of Hebei Medical University
RECRUITINGShijia Zhuang, China
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First Medical University and Shandong Provincial Qianfoshan Hospital
RECRUITINGJinan, China
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Harbin Medical University Cancer Hospital
RECRUITINGHarbin, China
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Liaoning Cancer Hospital and Institute
RECRUITINGShenyang, China
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Second Hospital of Hebei Medical University
RECRUITINGShijia Zhuang, China
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Shenzhen People's Hospita
RECRUITINGShenzhen, China
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Sichuan Provincial People's Hospital
RECRUITINGChendu, China
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YANBIAN University Hospital（Yanbian Hospital）
RECRUITINGYanbian, China
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the First Hospital of China Medical University
RECRUITINGShenyang, Liaoning, 110001, China
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