Kids' painkiller study aims for safer dosing

NCT ID NCT02044497

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how children aged 0-6 process the painkiller oxycodone after surgery. Researchers will measure drug levels in the blood and check certain genes that affect how the drug is broken down. The goal is to understand why some children may have more side effects or need different doses. About 68 children having specific surgeries will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
oral oxycodone
What this could lead to
If successful, this could help doctors give safer, more effective pain relief to children after surgery by tailoring doses based on genetics.
What could go wrong
This is a small, single-center study that only observes drug levels and genetics—it won't directly change treatment yet. Results may not apply to all children or surgeries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Boston Children Hospital

    Boston, Massachusetts, 02115, United States