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Which antifungal cream works best for stubborn skin fungus? a Head-to-Head trial aims to find out

NCT ID NCT07718685

Disease control Sponsor: Shalamar Institute of Health Sciences Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time

Summary

This trial compares two common antifungal creams — oxiconazole 1% and clotrimazole 1% — to see which works better for treating dermatophytosis, a fungal skin infection often called ringworm. About 164 adults with mild to moderate infections will apply one of the creams daily. The goal is to find out which cream clears the rash, itching, and scaling more completely.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
oxiconazole 1% cream or clotrimazole 1% cream
What this could lead to
If oxiconazole proves more effective, it could offer a better topical option for treating common fungal skin infections.
What could go wrong
This is a small, single-center trial comparing two existing drugs, so any advantage may be modest or not generalizable. Allergic reactions or skin irritation are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

164 people

The number who actually took part.

Started

Jan 2025

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years and above * Patients diagnosed with dermatophytosis per operational definition, involving less than 10% body surface area, that does not necessitate oral antifungal treatment (as assessed by the researcher). * Both males and females. Exclusion Criteria: * History of hypersensitivity to azole drugs or vehicle ingredients. * Use of any antifungal agents within past four weeks. * Use of topical corticoseroids within past two weeks. * Pregnant and lactating mothers.

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Conditions

The condition(s) this trial relates to.

dermatophytosis Tinea

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dermatophytoses

Contacts and locations

Locations

  • Shalamar hospital

    Lahore, Punjanb, 54840, Pakistan