Could a single dose beat brain worms? new trial aims to find out

NCT ID NCT06565507

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a drug called oxfendazole for people with mild brain cysticercosis, a parasitic infection that can cause seizures. Researchers will compare a single dose and three doses of oxfendazole against the standard combination therapy. The goal is to see if oxfendazole clears the parasites better and reduces seizure relapses. The trial plans to enroll 544 adults aged 18 to 75.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
oxfendazole
What this could lead to
If it works, this could provide a simpler, single-dose treatment for brain cysticercosis, reducing the need for longer drug regimens.
What could go wrong
This is a Phase 2/3 trial, so results are not yet known. The drug may not work better than current treatments, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cysticercosis Neurocysticercosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.