New combo therapy aims to fight back against recurrent ovarian cancer

NCT ID NCT05335993

First seen Apr 05, 2026 · Last updated Apr 10, 2026 · Updated 1 time

Summary

This study is testing whether adding an experimental drug called oregovomab to an existing cancer drug, niraparib, can help control recurrent ovarian cancer. It will involve about 10 women whose cancer returned but initially responded well to platinum-based chemotherapy. The main goal is to see if this combination can stop the cancer from growing for at least 12 to 24 weeks while monitoring side effects.

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Contacts and locations

Locations

  • Duke Cancer Center

    Durham, North Carolina, 27710, United States

  • Stephenson Cancer Center- University of Oklahoma Health Sciences Center

    Oklahoma City, Oklahoma, 73104, United States

  • University of Virginia Health System

    Charlottesville, Virginia, 22903, United States

Conditions

Explore the condition pages connected to this study.