New triple therapy takes on resistant ovarian cancer

NCT ID NCT05467670

First seen Mar 11, 2026 · Last updated May 17, 2026 · Updated 10 times

Summary

This study tests a new combination of drugs for people with ovarian cancer that has come back and no longer responds to platinum-based chemotherapy. The treatment adds ALX148 (which targets a protein called CD47 on cancer cells) to standard chemotherapy (liposomal doxorubicin) and an immunotherapy drug (pembrolizumab). The goal is to see if this mix can shrink tumors or slow the cancer. The study enrolled 16 adults with specific types of ovarian cancer and is currently active but not recruiting new participants.

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Contacts and locations

Locations

  • UPMC Hillman Cancer Center

    Pittsburgh, Pennsylvania, 15232, United States

Conditions

Explore the condition pages connected to this study.