New triple therapy targets hard-to-treat ovarian cancer
NCT ID NCT05467670
First seen Jun 27, 2026 · Last updated Jul 22, 2026 · Updated 2 times
Summary
This study tests a combination of three drugs—ALX148, liposomal doxorubicin, and pembrolizumab—in people with recurrent ovarian cancer that no longer responds to platinum-based chemotherapy. The goal is to see if blocking the CD47 protein on cancer cells can boost the immune system's ability to shrink tumors. Sixteen participants are enrolled in this phase 2 trial.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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UPMC Hillman Cancer Center
Pittsburgh, Pennsylvania, 15232, United States
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