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Tears may reveal how bodywork affects immunity

NCT ID NCT07633496

Knowledge-focused Sponsor: Lake Erie College of Osteopathic Medicine Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
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Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
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First seen Jun 27, 2026 · Last updated Aug 26, 2026 · Updated 3 times

Summary

This pilot study tests whether osteopathic manipulative treatment (OMT) — a hands-on therapy — can alter the concentration of certain proteins in human tears. Researchers will measure tear proteins linked to immunity and inflammation in healthy adults before and after OMT or a sham procedure. The goal is to see if this gentle bodywork might influence the body's immune or inflammatory state.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Osteopathic Manipulative Treatment (OMT)
What this could lead to
If OMT alters tear proteins, it could suggest a non-invasive way to influence immune or inflammatory responses in the body.
What could go wrong
This is a small pilot study in healthy volunteers, so results may not apply to people with medical conditions. The effect on tear proteins may be minimal or absent.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Individuals older than 18 years of age at the time of enrollment * Individuals that understand the study procedures and provide voluntary, informed consent * Individuals willing and able to receive Osteopathic Manipulative Treatment Exclusion Criteria: * Individuals younger than 18 years of age * Individuals who are pregnant or lactating * Individuals with infection or inflammatory conditions * Individuals physically unable to receive Osteopathic Manipulative Treatment * Individuals with dental or oral infection or surgery within the preceding 30 days.

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Conditions

The condition(s) this trial relates to.

Lacerations

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

No disease or condition is being directly studied The focus of the study in healthy volunteers

How to take part

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  1. The places running it

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  2. The official record

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Contacts and locations

Locations

  • Plaza 38 Medical Offices

    Erie, Pennsylvania, 16506, United States

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