Lung cancer trial: could adding chemo to targeted therapy buy more time?

NCT ID NCT04769388

First seen Jan 12, 2026 · Last updated May 24, 2026 · Updated 25 times

Summary

This study looks at people with advanced non-small cell lung cancer that has a specific EGFR gene change. After 3 weeks on the standard targeted drug osimertinib, those whose cancer still shows the gene change in their blood are randomly assigned to either keep taking osimertinib alone or add two chemotherapy drugs (carboplatin and pemetrexed). The goal is to see if the combination helps delay cancer growth longer. About 80 adults with good performance status are taking part.

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Contacts and locations

Locations

  • Cancer Hospital Chinese Academy of Medical Sciences

    Beijing, China

Conditions

Explore the condition pages connected to this study.