New PD-1 blocker aims to shrink advanced tumors

NCT ID NCT05751798

First seen Oct 31, 2025 · Last updated May 16, 2026 · Updated 26 times

Summary

This study tests a new drug called OSE-279 that blocks PD-1, a protein that can stop the immune system from attacking cancer. It is for people with advanced solid tumors or lymphomas that have not responded to other treatments. The study has three parts: first finding a safe dose, then testing safety and effectiveness alone or with another drug. About 41 adults will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Antwerp University Hospital

    NOT_YET_RECRUITING

    Edegem, 11013, Belgium

  • Centre Eugène Marquis

    COMPLETED

    Rennes, 35000, France

  • Centre Léon Bérard

    RECRUITING

    Lyon, 69373, France

  • Hopital Saint Joseph

    RECRUITING

    Paris, 75014, France

  • Hospital Regional Universitario de Málaga

    RECRUITING

    Málaga, 2901, Spain

  • Institut Gustave Roussy

    RECRUITING

    Villejuif, 94805, France

  • Institut Jules Bordet

    RECRUITING

    Anderlecht, 1070, Belgium

  • Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta (IDIBGI)

    RECRUITING

    Girona, 17007, Spain

  • Institut de Cancerologie de l'Ouest

    RECRUITING

    Saint-Herblain, 44805, France

  • Oncopole

    RECRUITING

    Toulouse, 31059, France

  • University Hospital A Coruña Biomedical Research Institute (INIBIC)

    RECRUITING

    A Coruña, Spain

Conditions

Explore the condition pages connected to this study.