One shot wonder? new antibiotic trial for Kids' skin infections
NCT ID NCT05599295
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a single dose of the antibiotic oritavancin in 118 children aged 3 months to 12 years with acute bacterial skin infections. The goal was to see if it is safe and tolerable. Researchers also looked at how the drug works in the body and whether it cures the infection.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- oritavancin (antibiotic)
- What this could lead to
- If successful, this could provide a single-dose treatment option for children with bacterial skin infections, reducing the need for multiple doses.
- What could go wrong
- This is a phase 2 trial with only 118 participants, so results may not apply to all children. Side effects are possible, and the drug may not work as well as current treatments.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Attikon University General Hospital
Chaïdári, Attica, 124 62, Greece
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Brasov Children Clinical Hospital
Brasov, 500063, Romania
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Centro Hospitalar de Lisboa Ocidental, EPE - Hospital São Francisco Xavier
Lisbon, 1449-005, Portugal
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Children's Clinical University Hospital
Riga, LV-1004, Latvia
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Daugavpils Regional Hospital
Daugavpils, Daugavpils Aprinkis, LV-5417, Latvia
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Hippokratio General Hospital of Thessaloniki
Thessaloniki, 546 42, Greece
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Hospital Sant Joan de Deu - PIN
Barcelona, 8950, Spain
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Hospital Universitario 12 de Octubre
Madrid, 28041, Spain
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Hospital Universitario La Paz - PPDS
Madrid, 28046, Spain
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Hospital Universitario Vall d'Hebron - PPDS
Barcelona, 8035, Spain
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Hospital de Cascais
Alcabideche, Lisbon District, 2755-009, Portugal
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Hospital of Lithuanian University of Health Sciences Kauno klinikos
Kaunas, Kaunas County, LT-50009, Lithuania
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Klaipeda Children Hospital
Klaipėda, Klaipėda County, 92140, Lithuania
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Louis Turcanu Emergency Clinical Hospital for Children
Timișoara, Timiș County, 300011, Romania
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Multiprofile Hospital For Active Treatment Dr Tota Venkova
Gabrovo, 5300, Bulgaria
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Multiprofile Hospital for Active Treatment- Sveti Nikolay Chudotvoretz - LOM EOOD
Lom, Montana, 3600, Bulgaria
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Nationwide Children's Hospital
Columbus, Ohio, 43205-2664, United States
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Papageorgiou General Hospital of Thessaloniki
Thessaloniki, 56429, Greece
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Tampa General Hospital
Tampa, Florida, 33606, United States
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University Multiprofile Hospital For Active Treatment Kanev AD
Rousse, 7002, Bulgaria
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University Multiprofile Hospital for Active Treatment - Prof. Dr. Stoyan Kirkovich AD
Stara Zagora, 6003, Bulgaria
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University Multiprofile Hospital for Active Treatment Sveti Georgi EAD-66 Peshtersko Shosse blvd
Plovdiv, 4000, Bulgaria
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University Multiprofile Hospital for Active Treatment and Emergency Medicine N. I. Pirogov EAD
Sofia, 1606, Bulgaria