One shot wonder? new antibiotic trial for Kids' skin infections

NCT ID NCT05599295

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a single dose of the antibiotic oritavancin in 118 children aged 3 months to 12 years with acute bacterial skin infections. The goal was to see if it is safe and tolerable. Researchers also looked at how the drug works in the body and whether it cures the infection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

oritavancin (antibiotic)

What this could lead to

If successful, this could provide a single-dose treatment option for children with bacterial skin infections, reducing the need for multiple doses.

What could go wrong

This is a phase 2 trial with only 118 participants, so results may not apply to all children. Side effects are possible, and the drug may not work as well as current treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

skin infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Attikon University General Hospital

    Chaïdári, Attica, 124 62, Greece

  • Brasov Children Clinical Hospital

    Brasov, 500063, Romania

  • Centro Hospitalar de Lisboa Ocidental, EPE - Hospital São Francisco Xavier

    Lisbon, 1449-005, Portugal

  • Children's Clinical University Hospital

    Riga, LV-1004, Latvia

  • Daugavpils Regional Hospital

    Daugavpils, Daugavpils Aprinkis, LV-5417, Latvia

  • Hippokratio General Hospital of Thessaloniki

    Thessaloniki, 546 42, Greece

  • Hospital Sant Joan de Deu - PIN

    Barcelona, 8950, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, 28041, Spain

  • Hospital Universitario La Paz - PPDS

    Madrid, 28046, Spain

  • Hospital Universitario Vall d'Hebron - PPDS

    Barcelona, 8035, Spain

  • Hospital de Cascais

    Alcabideche, Lisbon District, 2755-009, Portugal

  • Hospital of Lithuanian University of Health Sciences Kauno klinikos

    Kaunas, Kaunas County, LT-50009, Lithuania

  • Klaipeda Children Hospital

    Klaipėda, Klaipėda County, 92140, Lithuania

  • Louis Turcanu Emergency Clinical Hospital for Children

    Timișoara, Timiș County, 300011, Romania

  • Multiprofile Hospital For Active Treatment Dr Tota Venkova

    Gabrovo, 5300, Bulgaria

  • Multiprofile Hospital for Active Treatment- Sveti Nikolay Chudotvoretz - LOM EOOD

    Lom, Montana, 3600, Bulgaria

  • Nationwide Children's Hospital

    Columbus, Ohio, 43205-2664, United States

  • Papageorgiou General Hospital of Thessaloniki

    Thessaloniki, 56429, Greece

  • Tampa General Hospital

    Tampa, Florida, 33606, United States

  • University Multiprofile Hospital For Active Treatment Kanev AD

    Rousse, 7002, Bulgaria

  • University Multiprofile Hospital for Active Treatment - Prof. Dr. Stoyan Kirkovich AD

    Stara Zagora, 6003, Bulgaria

  • University Multiprofile Hospital for Active Treatment Sveti Georgi EAD-66 Peshtersko Shosse blvd

    Plovdiv, 4000, Bulgaria

  • University Multiprofile Hospital for Active Treatment and Emergency Medicine N. I. Pirogov EAD

    Sofia, 1606, Bulgaria