Mini tumors in a dish could pick the right drug for bile duct cancer

This study tests a new way to choose cancer drugs for people with advanced biliary tract cancer that cannot be removed by surgery. Doctors will take a small sample of the tumor, grow it in the lab as a mini-organoid, and test different drug combinations to see which works best. 88 participants will either get standard treatment or a treatment chosen based on organoid test results. The goal is to see if this personalized approach leads to better tumor shrinkage and longer time without cancer growth.