Brain chemical blocked to unlock secrets of depression
NCT ID NCT07267559
First seen Jan 09, 2026 · Last updated May 25, 2026 · Updated 19 times
Summary
This study looks at how a brain chemical called orexin affects emotions and learning. Healthy adults aged 18 to 40 will take a single dose of daridorexant (which blocks orexin) or a placebo. They will then complete computer tasks to measure emotional processing and learning. The goal is to better understand mental health conditions like depression and anxiety.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Department of Psychiatry, University of Oxford
RECRUITINGOxford, OX3 7JX, United Kingdom
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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