New hope for lymphoma patients: drug combo shows promise in phase 3 trial

NCT ID NCT05051891

First seen Apr 09, 2026 · Last updated Apr 24, 2026 · Updated 3 times

Summary

This study tested whether adding the drug orelabrutinib to standard chemotherapy (R-CHOP) works better than chemotherapy alone for people with untreated mantle cell lymphoma. Only 3 patients took part. The main goal was to see if the combination delays cancer growth. This is a disease-control approach, not a cure.

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Contacts and locations

Locations

  • Anhui Province Cancer Hospital

    Hefei, Anhui, 230009, China

  • Beijing Cancer Hospital

    Beijing, Beijing Municipality, 100143, China

  • Guangzhou First People's Hospital

    Guangzhou, Guangdong, 510180, China

  • Henan Tumor Hospital

    Zhengzhou, Henan, 450008, China

  • Hospital of Hematology, Chinese Academy of Medical Sciences

    Tianjin, Tianjin Municipality, 300052, China

  • Jiangsu Province Hospital

    Nanjing, Jiangsu, 210029, China

  • Shandong Provincial Hospital

    Jinan, Shandong, 250021, China

  • Sun Yat-sen University Cancer Center

    Guangzhou, Guangdong, 510060, China

  • The First Affiliated Hospital of Guangxi Medical University

    Guangxi, Nanning, 530021, China

  • The First Affiliated Hospital of Nanchang University

    Nanchang, Jiangxi, 3300008, China

  • The First Affiliated Hospital of Soochow University

    Suzhou, Jiangsu, 215006, China

  • The First Affiliated Hospital of Xiamen University

    Xiamen, Fujian, 361003, China

  • The First Affiliated Hospital of Zhengzhou University

    Zhengzhou, Henan, 450052, China

  • The First Hospital of China Medical University

    Shenyang, Liaojing, 110001, China

  • The First Hospital of Jilin University

    Changchun, Jilin, 130021, China

  • The Fourth Hospital of Hebei Medical University

    Shijiazhuang, Hebei, 50011, China

  • Tianjin Cancer Hospital

    Tianjin, Tianjin Municipality, 300060, China

  • Tumor in Hunan Province

    Hunan, Changsha, 410013, China

  • West China Hospital,Sichuan University

    Chengdu, Sichuan, 610041, China

  • Wuhan Union Hospital

    Wuhan, Hubei, 430022, China

  • Zhejiang Cancer Hospital

    Hangzhou, Zhejiang, 310022, China

  • he First Affiliated Hospital of Zhengjiang University

    Hangzhou, Zhejiang, 310003, China

Conditions

Explore the condition pages connected to this study.