New drug cocktail aims to shrink brain tumors

NCT ID NCT07185373

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 26 times

Summary

This study tests whether adding the targeted drug orelabrutinib to standard chemotherapy improves outcomes for people newly diagnosed with primary central nervous system lymphoma (a rare brain cancer). About 215 adults aged 18-75 will be randomly assigned to one of three treatment groups. The goal is to see which combination best shrinks tumors while keeping side effects manageable.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Hematology, Qilu Hospital of Shandong University

    Jinan, China

    Contact

  • West China Hospital of Sichuan University

    Chengdu, China

    Contact

Conditions

Explore the condition pages connected to this study.