Oregano oil may interfere with your meds, new study warns

NCT ID NCT06693960

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase trial at Washington State University is testing whether oregano supplements affect how the body breaks down common drugs. Sixteen healthy adults will take oregano oil alongside a cocktail of five drugs (caffeine, dextromethorphan, losartan, midazolam, and omeprazole). Researchers will measure drug levels in the blood to see if oregano changes their metabolism. The goal is to understand potential herb-drug interactions, not to treat any disease.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
oregano oil (dietary supplement)
What this could lead to
If it works, this could help people know whether taking oregano supplements changes how their medications work.
What could go wrong
This is a very small, early-phase study in healthy people, not patients. Results may not apply to everyone, and oregano might not affect drug metabolism at all.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Washington State University College of Pharmacy and Pharmaceutical Sciences

    RECRUITING

    Spokane, Washington, 99202, United States

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