Can a special dressing deepen the gum crease better than standard care?
NCT ID NCT07767682
First seen Aug 17, 2026 · Last updated Aug 18, 2026 · Updated 1 time
Summary
This trial tests whether adding a special absorbent dressing (oxidized regenerated cellulose) to the standard Clark vestibuloplasty procedure can increase the depth of the vestibular sulcus—the groove between the gums and cheek—more than the standard approach. About 36 healthy adults with insufficient sulcus depth will be randomly assigned to receive either the standard procedure with a periodontal dressing or the standard procedure plus the oxidized cellulose material. Researchers will measure sulcus depth and gum tissue before surgery and at 1 and 3 months after, and also track pain and painkiller use during the first week.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- oxidized regenerated cellulose (ORC) applied as a surgical dressing after vestibuloplasty
- What this could lead to
- If it works, this could offer a more comfortable and effective way to deepen the vestibular sulcus, potentially improving denture fit and oral function.
- What could go wrong
- This is a small, early-stage trial, so results may not be conclusive. The material could cause irritation or fail to improve outcomes compared to standard care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 36 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Jul 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Systemically healthy * Non-smoker * Insufficient vestibular sulcus depth * No regular medication use * Age 18 years or older * No previous vestibuloplasty in the same region * Not pregnant or breastfeeding * Willing to participate and able to provide written informed consent Exclusion Criteria: * Presence of a systemic disease * Regular use of systemic medication * Pregnancy or lactation * Smoking or alcohol use * Previous vestibuloplasty in the same region
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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İzmir Katip Çelebi University
RECRUITINGIzmir, Çiğli, 35620, Turkey (Türkiye)