New 'Smart' cancer drug seeks to target tumors without harsh side effects

NCT ID NCT05947474

Summary

This is an early-stage study to test the safety and find the right dose of a new investigational drug called ORB-011 for people with advanced solid tumors. The drug is designed to activate a powerful immune signal only inside specific immune cells near the tumor, aiming to fight cancer while avoiding body-wide side effects. The study will enroll about 55 adults with various advanced cancers who have already tried all standard treatments available to them.

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Contacts and locations

Locations

  • Honor Health Research Institute

    Scottsdale, Arizona, 85258, United States

  • MD Anderson Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.