New mouth rinse could tame the fire of spicy foods instantly
NCT ID NCT07630571
First seen Jun 27, 2026 · Last updated Aug 11, 2026 · Updated 4 times
Summary
This pilot study tests whether a special hyaluronan oral solution can quickly ease the burning and irritation caused by spicy foods like chili peppers. Fifty healthy adults will have their mouths exposed to capsaicin (the spicy chemical) and then rinse with the test solution or a control. Pain and irritation are measured at several time points up to 90 seconds. The goal is to see if this rinse offers fast, non-drug relief.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- 10% 35 kDa hyaluronan oral solution
- What this could lead to
- If it works, this could point toward a fast-acting, non-prescription rinse for soothing mouth pain or irritation from spicy foods or mild oral discomfort.
- What could go wrong
- This is a very early, small pilot study with only 50 healthy people. The pain is artificially induced, so results may not apply to real-world oral pain conditions. Also, it's open-label, which can bias results.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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HA35
Qingdao, Shandong, 266000, China
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