New mouth rinse could tame the fire of spicy foods instantly
NCT ID NCT07630571
First seen Jun 09, 2026
Summary
This pilot study tests whether a special hyaluronan oral solution can quickly ease the burning and irritation caused by spicy foods like chili peppers. Fifty healthy adults will have their mouths exposed to capsaicin (the spicy chemical) and then rinse with the test solution or a control. Pain and irritation are measured at several time points up to 90 seconds. The goal is to see if this rinse offers fast, non-drug relief.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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HA35
Qingdao, Shandong, 266000, China
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
10% 35 kDa hyaluronan oral solution
What this could lead to
If it works, this could point toward a fast-acting, non-prescription rinse for soothing mouth pain or irritation from spicy foods or mild oral discomfort.
What could go wrong
This is a very early, small pilot study with only 50 healthy people. The pain is artificially induced, so results may not apply to real-world oral pain conditions. Also, it's open-label, which can bias results.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.