Oral combo trial aims to control aggressive blood disorder

NCT ID NCT05782127

Summary

This early-stage study is testing the safety and initial effectiveness of a combination of two oral drugs, Onureg and Venetoclax, for people with untreated high-risk myelodysplastic syndrome (MDS) who cannot receive a stem cell transplant. The main goal is to find the safest and most effective dose and treatment schedule for future research. It will involve about 36 adult participants who have not had prior treatment for their MDS.

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Contacts and locations

Locations

  • CH Annecy Genevois

    Épagny, 74370, France

  • CH Le Mans

    Le Mans, 72037, France

  • CH Lyon sud

    Lyon, 69495, France

  • CH Valence

    Valence, 26000, France

  • CHI Mont-de-Marsan

    Mont-de-Marsan, 40000, France

  • CHU Hôtel Dieu

    Nantes, 44093, France

  • CHU Nîmes - Institut de Cancérologie du Gard

    Nîmes, 30029 cedex 9, France

  • CHU Saint Eloi

    Montpellier, 34295, France

  • CHU d'Amiens Picardie - Site sud

    Amiens, 80054, France

  • CHU d'Angers

    Angers, 49033, France

  • CHU de Grenoble

    Grenoble, 38043, France

  • CHU de Haut-Lévèque

    Pessac, 33604, France

  • CHU de Limoges - Hôpital Dupuytren

    Limoges, 87042, France

  • CHU de Poitiers

    Poitiers, 86021, France

  • CHU de Tours - Hôpital Bretonneau

    Tours, 37000, France

  • Centre Henri Becquerel

    Rouen, 76038, France

  • Hôpital Archet 1

    Nice, 06200, France

  • Hôpital Avicenne

    Bobigny, 93009, France

  • Hôpital Brabois

    Vandœuvre-lès-Nancy, 54500, France

  • Hôpital Cochin

    Paris, 75014, France

  • Hôpital Saint Louis

    Paris, 75010, France

  • Hôpital Saint Vincent de Paul

    Lille, 59020, France

  • Hôpital privé Sévigné

    Cesson-Sévigné, 35510, France

  • IUCT Oncopole

    Toulouse, 31059, France

  • Institut Paoli Calmettes

    Marseille, 13009, France

Conditions

Explore the condition pages connected to this study.