Toothbrush showdown: which keeps ICU Patients' mouths healthiest?
NCT ID NCT07200297
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests three ways to clean the mouth of intensive care patients using a non-invasive breathing mask. Sixty adults will be randomly assigned to standard care, an electric toothbrush, or a manual toothbrush. The goal is to see which method best prevents mouth problems and keeps oral health in good shape.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Apr 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Must be in an intensive care unit * Must have consented to participate in the study from themselves or their family * Must be over 18 years of age * Must be on a non-invasive mechanical ventilator * Must have no known active infection. * Must be in a stable state of consciousness and able to communicate. * Must be expected to remain in intensive care for at least 48 hours. Exclusion Criteria: * Intubated patients. * Patients with severe oral infections or bleeding mucosal wounds. * Those receiving radiotherapy/chemotherapy to the head and neck region. * Organ transplant patients. * Patients without oral anatomic abnormalities or dentures. * Those who refused to participate in the study or did not sign the consent form. * Patients with chronic or acute health conditions that prevent oral hygiene.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Ataturk University
RECRUITINGErzurum, Merkez, 25240, Turkey (Türkiye)