New pill combo shows promise for rare blood cancer patients who Can't get transplant

NCT ID NCT05782127

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a combination of two oral medications, Onureg and Venclyxto, in people with a high-risk form of myelodysplastic syndromes (a blood cancer) who cannot have a stem cell transplant. The goal is to find the safest and most effective dose of Onureg when used with Venclyxto, and to see how well the combination works. About 36 adults will take part in this early-phase trial across multiple centers.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

myelodysplastic syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CH Annecy Genevois

    Épagny, 74370, France

  • CH Le Mans

    Le Mans, 72037, France

  • CH Lyon sud

    Lyon, 69495, France

  • CH Valence

    Valence, 26000, France

  • CHI Mont-de-Marsan

    Mont-de-Marsan, 40000, France

  • CHU Hôtel Dieu

    Nantes, 44093, France

  • CHU Nîmes - Institut de Cancérologie du Gard

    Nîmes, 30029 cedex 9, France

  • CHU Saint Eloi

    Montpellier, 34295, France

  • CHU d'Amiens Picardie - Site sud

    Amiens, 80054, France

  • CHU d'Angers

    Angers, 49033, France

  • CHU de Grenoble

    Grenoble, 38043, France

  • CHU de Haut-Lévèque

    Pessac, 33604, France

  • CHU de Limoges - Hôpital Dupuytren

    Limoges, 87042, France

  • CHU de Poitiers

    Poitiers, 86021, France

  • CHU de Tours - Hôpital Bretonneau

    Tours, 37000, France

  • Centre Henri Becquerel

    Rouen, 76038, France

  • Hôpital Archet 1

    Nice, 06200, France

  • Hôpital Avicenne

    Bobigny, 93009, France

  • Hôpital Brabois

    Vandœuvre-lès-Nancy, 54500, France

  • Hôpital Cochin

    Paris, 75014, France

  • Hôpital Saint Louis

    Paris, 75010, France

  • Hôpital Saint Vincent de Paul

    Lille, 59020, France

  • Hôpital privé Sévigné

    Cesson-Sévigné, 35510, France

  • IUCT Oncopole

    Toulouse, 31059, France

  • Institut Paoli Calmettes

    Marseille, 13009, France